Infarction of papillary muscles and mitral insufficiency associated with congenital aortic stenosis.

IN 21 INFANTS, each with symptomatic congenital aortic stenosis and left ventricular cavity of nearly normal size studied clinically,' evidence for mitral insuffiiegncy was frequently encountered. In five of the patients left ventriculography was done and, in each, mitral insufficiency was demonstrated. This background of experience led us to study, in particular, the mitral valve in specimens of heart from infants with congenital aortic stenosis. This study led to the conclusion that there is a common association between congenital aortic stenosis, on one hand, and infarction of the papillary muscles of the mitral valve, with resulting mitral insufficiency, on the other. It is the purpose of this report to describe the pathological features of this combination of lesions as a means of emphasizing its occurrence.